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The role of wild birds in the global highly pathogenic avian influenza H5 panzootic

Published 7 months agoVersion 1arXiv:2504.11910

Authors

Manon Couty, Claire Guinat, Diletta Fornasiero, François-Xavier Briand, Pierre-Yves Henry, Béatrice Grasland, Loïc Palumbo, Guillaume Le Loc'h

Categories

q-bio.PE

Abstract

The highly pathogenic avian influenza (HPAI) H5 clade 2.3.4.4b has triggered an unprecedented global panzootic. As the frequency and scale of HPAI H5 outbreaks continue to rise, understanding how wild birds contribute to shape the global virus spread across regions, affecting poultry, domestic and wild mammals, is increasingly critical. In this review, we examine ecological and evolutionary studies to map the global transmission routes of HPAI H5 viruses, identify key wild bird species involved in viral dissemination, and explore infection patterns, including mortality and survival. We also highlight major remaining knowledge gaps that hinder a full understanding of wild birds role in viral dynamics, which must be addressed to enhance surveillance strategies and refine risk assessment models aimed at preventing future outbreaks in wildlife, domestic animals and safeguard public health.

The role of wild birds in the global highly pathogenic avian influenza H5 panzootic

7 months ago
v1
8 authors

Categories

q-bio.PE

Abstract

The highly pathogenic avian influenza (HPAI) H5 clade 2.3.4.4b has triggered an unprecedented global panzootic. As the frequency and scale of HPAI H5 outbreaks continue to rise, understanding how wild birds contribute to shape the global virus spread across regions, affecting poultry, domestic and wild mammals, is increasingly critical. In this review, we examine ecological and evolutionary studies to map the global transmission routes of HPAI H5 viruses, identify key wild bird species involved in viral dissemination, and explore infection patterns, including mortality and survival. We also highlight major remaining knowledge gaps that hinder a full understanding of wild birds role in viral dynamics, which must be addressed to enhance surveillance strategies and refine risk assessment models aimed at preventing future outbreaks in wildlife, domestic animals and safeguard public health.

Authors

Manon Couty, Claire Guinat, Diletta Fornasiero et al. (+5 more)

arXiv ID: 2504.11910
Published Apr 16, 2025

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